Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver
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چکیده
منابع مشابه
Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver.
Obesity is typically associated with resistance to leptin, yet the mechanism by which leptin signaling becomes impaired is poorly understood. Here we sought to determine if the development of obesity and leptin resistance correlates with increased expression of protein tyrosine phosphatase 1B (PTP1B) in peripheral tissues and whether over-expression of this phosphatase, specifically in liver, c...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2006
ISSN: 0952-5041,1479-6813
DOI: 10.1677/jme.1.01937